Sunday, May 12, 2013

THE ROUGH ROAD TO HUMANIZATION

The hypothesis of genetic determinism I embrace puts me in direct conflict with many people; if that were a true statement, it would have dire consequences for humankind. While indications clear show genes control our behavior, they also show that we can modify that behavior albeit to a limited degree. The major thrust of the opposition is the claim we have free will; therefore, our behavior cannot be control by our genes.


My argument starts from with the idea that behavior is genetically controlled. Chickens look and behave like chicken, dogs look and behave like dogs and people look and behave like people, which is irrefutable. The first implication of this is that our behavior, like our physical form, results from adaptive evolution. Scientists recognize the existence of cultural universals, which evolution has shaped by adaptation and buried in our genes, just as they recognize common physical features are genetic.

Cultural universals are behaviors common to all people in the world. It is enlightening to recognize there are geographical physical as well as cultural differences in people. There is a lack of understanding about how adaption by natural selection tested by survival of the fittest could shape sophisticated culture. This implies we somehow genetically embed behavior we “learned” about survival and quality of life as culture but also recognize there are things we learn that we have not embedded in our genomes. The Eskimo culture and Inuit appearance is not the same as the culture and appearance of an indigenous Amazonian, yet indisputably, people look like and act like people.

We can layer short term learning on top of this cultural hierarchy; the idea that we know our mother’s face as well as the way to the local grocery store, and our way to work. We also remember that we read a newspaper yesterday but have forgotten what it was we read. All of this falls under the rubric of behavior. Clearly, somewhere between cultural universal and short-term memory we switch from accumulated memory, as written in our DNA/RNA, and the ability to learn and remember things. Memory and learning (the desire to learn) are also genetic. To make the point concerning the interface between accumulated genetic knowledge (DNA/RNA), the genetic directed ability to learn and actually learning, we can take college courses about how to learn. Thus, we commonly recognize that we as individuals can modify our genetic ability to learn and remember things but do not know how to modify our children’s ability to learn and remember things; however, there must be a way, which seems the only rational explanation for cultural universals.

What is in our genes and what we learn, is not always good and beneficial. We know what we learn is not always good but in contrast there seems to be a commonly held fallacy, which is that if we established something in our DNA/RNA be natural selection (adaptive learning) it is all good when it clearly is not. Obviously, to a biologist, the course of survival is paved with mutations that benefit survival, which I assume sets the stage for this kind of thinking. If a mutation is damages to our survival it is sooner or later lost in the trial and error battle for survival but also if the mutation does no harm it may exist in our DNA/RNA that is trans-generational. The blow back is that if either good or bad behavior is our genome, under some circumstances it is there forever, and we cannot change it short of some modern laboratory manipulation of DNA/RNA. Scientists are working to be able to modify genomes of people genetically with disease including mental disease. Some people are advocating eugenics to better the human race through learned selection—people make mating decisions from what they have learned—encouraging people with the best “genes” to have children. In one sense, this has been going on for several millions years. In extreme examples, from the past, such decisions were under State control with disastrous consequences.

The irrefutable lesson we can learn from all of this is that genetically determined behavior is the responsibility of that individual who carries the gene(s), just like learned behavior. It is yours and no one else’s: an awesome responsibility. This is becoming more and more precise: because of the scientific unraveling of the human genome, a specific cluster of genes can be accurately associated with an anatomic or metabolic change, disease or behavior: cause and effect. If we have a genetic disease, and there are more and more of them identified every year, we suffer the consequences; some may be lethal some not so much. The same consideration holds for what we learned, meaning what we learn can be lethal—suicide, war, or a man being caught with the wrong woman—by her husband. We just established that behavior is: 1) learned, 2) genetic but modifiable by learning, or 3) genetic and un-modifiable. At least with the current state of knowledge, it is un-modifiable. What do we do about ill effects of genetic origin on survival and quality of life? Do we step back and allow natural selection to take place; let the sick die; thus, let the fittest live. The choice we have made as a species seems obvious; we treat disease and transplant failed organs everyday. We keep the infirm alive for years, we do genetic counseling; in contrast, we abhor eugenics, use the death penalty, and we fight wars. In addition, everyday we modify not only our own behavior but also the behavior of others.

We often deny genetic determinism because our egos don’t allow us to believe we do not have free will. We do have limited free will, but it does not extend to all behavior; it is not all or nothing. I refer the reader to the concept of cultural universals (on the internet) and encourage them to digest the implications of each item on the long list in terms of you own personal behavior. Thus, the only conclusion possible seems that we do much more in common than just react to a biota wide sense of self-preservation: fear, fight, flight, to hot and cold, thirst and hunger. We also react to genetically embedded feelings such as sympathy, empathy, shame, and pride woven into complex relationship: hate, love, gregariousness, hierarchy dominance, and an arm long string of etceteras including marriage and burial rituals all of which mold society into sophisticated culture. Among other things, we act like men act or we act like women act in families, we fall into an ordered religious, political, and business hierarchy as leaders or followers in society, and blend into what I consider as the broad sweep of instinctual behavior embedded in our genome, which is guided by but not controlled by current “learned behavior”. In other word, we are using our current learning to molding our species genes. Scientists are not sure how this happens, but molding genomes by changing gene frequency by allele selection seems to be the currently popular mechanism.

Learning blends into instincts just as geographic learning blends into cultural universals. There is an interface, even if it is ill-define. Racism, politics, male dominance, greed and selfishness, persistence, aggression, hierarchy dominance, kin selection are just an unordered smattering of examples related to determinism. The premise here is that we can learn to modify genomes; hence, our deterministic behavior. The hypothesis is that genetic behavior may be deterministic but it is modifiable. There is great hope in that. To make the point in a mind numbing way, I will use a horrifying example, cannibalism. For early knuckle dragging Homo sapiens, bestial cannibalism was a common practice. To day, we find the practice reprehensible even in rare and extreme circumstances. I see evidence every day we are learning how to avoid and even how to shun completely reprehensible deterministic behaviors, equally horrific in its day as cannibalism was: racism, male dominance, war, homicide, and violence in general, which is the road to our humanization we started as early as two million years ago but certainly by 100,000 years ago. We will not lift ourselves completely out of our bestial past in the near future but once we triumph over greed, we will have succeeded. We will not have conquered our genome but we will have learned how to live with it the best way we can.    

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